Crema to Palermo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Crema and arrive at Palermo Notarbartolo every about 2 hours on average. If travelling with Trenitalia, you need to know the Crema to Palermo train schedule: the first train leaves at 13:29, while the last ride is at 20:30. A Crema to Palermo train cost about 112.6 €. But how long is the train ride from Crema to Palermo? Your journey takes about 21 hours on average.