Cremona to Syracuse trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Cremona and arrive at Siracusa every about 2 hours on average. If travelling with Trenitalia, you need to know the Cremona to Syracuse train schedule: the first train leaves at 06:58, while the last ride is at 17:30. A Cremona to Syracuse train cost about 106.9 €. But how long is the train ride from Cremona to Syracuse? Your journey takes about 18 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Cremona to Syracuse and find low cost tickets starting from 75 €!