Desenzano del Garda to Alessandria trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Desenzano del Garda-Sirmione and arrive at Alessandria every 60 minutes on average. If travelling with Trenitalia, you need to know the Desenzano del Garda to Alessandria train schedule: the first train leaves at 06:07, while the last ride is at 22:07. A Desenzano del Garda to Alessandria train cost about 14.95 €. But how long is the train ride from Desenzano del Garda to Alessandria? Your journey takes about 4 hours on average.