Desio to Enna trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Desio and arrive at Enna every about 6 hours on average. If travelling with Trenitalia, you need to know the Desio to Enna train schedule: the first train leaves at 16:24, while the last ride is at 18:09. A Desio to Enna train cost about 230.85 €. But how long is the train ride from Desio to Enna? Your journey takes about 17 hours on average.