Desio to Genoa trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Desio and arrive at Genova Piazza Principe every 60 minutes on average. If travelling with Trenitalia, you need to know the Desio to Genoa train schedule: the first train leaves at 07:02, while the last ride is at 07:02. A Desio to Genoa train cost about 23.0 €. But how long is the train ride from Desio to Genoa? Your journey takes about 3 hours on average.