Desio to Noto trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Desio and arrive at Noto every about 4 hours on average. If travelling with Trenitalia, you need to know the Desio to Noto train schedule: the first train leaves at 16:24, while the last ride is at 19:24. A Desio to Noto train cost about 77.45 €. But how long is the train ride from Desio to Noto? Your journey takes about 19 hours on average.