Desio to Trieste trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Desio and arrive at Trieste Centrale every 60 minutes on average. If travelling with Trenitalia, you need to know the Desio to Trieste train schedule: the first train leaves at 06:09, while the last ride is at 21:39. A Desio to Trieste train cost about 36.85 €. But how long is the train ride from Desio to Trieste? Your journey takes about 6 hours on average.