To get from Domodossola a Casarano by train you can catch one of the 32 trains that everyday travel between Domodossola and Lecce, the closest station to the city. For your trip from Domodossola to Lecce by train you can choose to leave from one of Domodossola main stations: Domodossola, Salerno If travelling with Trenitalia, you need to know the Domodossola to Lecce train schedule: the first train leaves at 04:54, while the last ride is at 18:54. A Domodossola to Lecce train cost about 19.85 €. But how long is the train ride from Domodossola to Lecce? Your journey takes about 8 hours on average.