Domodossola to Noto trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Domodossola and arrive at Noto every about 2 hours on average. If travelling with Trenitalia, you need to know the Domodossola to Noto train schedule: the first train leaves at 12:54, while the last ride is at 19:58. A Domodossola to Noto train cost about 119.35 €. But how long is the train ride from Domodossola to Noto? Your journey takes about 11 hours on average.