Empoli to Alessandria trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 12 daily rides to get from Empoli to Alessandria. Trains leave from Empoli and arrive at Alessandria every 60 minutes on average. If travelling with Trenitalia, you need to know the Empoli to Alessandria train schedule: the first train leaves at 01:15, while the last ride is at 17:58. A Empoli to Alessandria train cost about 23.9 €. But how long is the train ride from Empoli to Alessandria? Your journey takes about 5 hours on average.