Empoli to Ancona trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Empoli and arrive at Ancona every 60 minutes on average. If travelling with Trenitalia, you need to know the Empoli to Ancona train schedule: the first train leaves at 06:18, while the last ride is at 20:41. A Empoli to Ancona train cost about 38.3 €. But how long is the train ride from Empoli to Ancona? Your journey takes about 4 hours on average.