Empoli to Caltagirone trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Empoli and arrive at Caltagirone every about 6 hours on average. If travelling with Trenitalia, you need to know the Empoli to Caltagirone train schedule: the first train leaves at 01:15, while the last ride is at 19:32. A Empoli to Caltagirone train cost about 119.9 €. But how long is the train ride from Empoli to Caltagirone? Your journey takes about 20 hours on average.