Enna to Alessandria trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Enna and arrive at Alessandria every about 4 hours on average. If travelling with Trenitalia, you need to know the Enna to Alessandria train schedule: the first train leaves at 11:28, while the last ride is at 18:24. A Enna to Alessandria train cost about 94.75 €. But how long is the train ride from Enna to Alessandria? Your journey takes about 22 hours on average.