Fano to Messina trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Fano and arrive at Messina Centrale every about 2 hours on average. If travelling with Trenitalia, you need to know the Fano to Messina train schedule: the first train leaves at 07:08, while the last ride is at 21:17. A Fano to Messina train cost about 99.35 €. But how long is the train ride from Fano to Messina? Your journey takes about 14 hours on average.