Fano to Niscemi trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Fano and arrive at Niscemi every about 6 hours on average. If travelling with Trenitalia, you need to know the Fano to Niscemi train schedule: the first train leaves at 14:42, while the last ride is at 21:17. A Fano to Niscemi train cost about 124.5 €. But how long is the train ride from Fano to Niscemi? Your journey takes about 1 hour on average.