Fermo to Niscemi trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Porto S. Giorgio-Fermo and arrive at Niscemi every about 12 hours on average. If travelling with Trenitalia, you need to know the Fermo to Niscemi train schedule: the first train leaves at 14:16, while the last ride is at 14:16. A Fermo to Niscemi train cost about 153.7 €. But how long is the train ride from Fermo to Niscemi? Your journey takes about 2 hours on average.