Fermo to Palermo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Porto S. Giorgio-Fermo and arrive at Palermo Notarbartolo every about 2 hours on average. If travelling with Trenitalia, you need to know the Fermo to Palermo train schedule: the first train leaves at 12:13, while the last ride is at 20:27. A Fermo to Palermo train cost about 98.0 €. But how long is the train ride from Fermo to Palermo? Your journey takes about 22 hours on average.