Florence to Agrigento trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 2 daily rides to get from Florence to Agrigento. Trains leave from Firenze S. M. Novella and arrive at Agrigento Centrale every about 6 hours on average. The trip by train from Florence to Agrigento last on average 17:16 travelling with high-speed trains (Frecciarossa or Italotreno) If travelling with Trenitalia, you need to know the Florence to Agrigento train schedule: the first train leaves at 20:38, while the last ride is at 20:38. A Florence to Agrigento train cost about 125.25 €. But how long is the train ride from Florence to Agrigento? Your journey takes about 17 hours on average. Thanks to Trenitalia offers, you can save on your trip from Florence to Agrigento and find prices starting from 59 €!