Florence to Caltagirone trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Firenze S. M. Novella and arrive at Caltagirone every about 2 hours on average. If travelling with Trenitalia, you need to know the Florence to Caltagirone train schedule: the first train leaves at 10:19, while the last ride is at 21:09. A Florence to Caltagirone train cost about 94.65 €. But how long is the train ride from Florence to Caltagirone? Your journey takes about 15 hours on average.