Frascati to Messina trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Tor Vergata and arrive at Messina Centrale every about 2 hours on average. If travelling with Trenitalia, you need to know the Frascati to Messina train schedule: the first train leaves at 06:34, while the last ride is at 21:26. A Frascati to Messina train cost about 62.5 €. But how long is the train ride from Frascati to Messina? Your journey takes about 9 hours on average.