To get from Frosinone a Casarano by train you can catch one of the 4 trains that everyday travel between Frosinone and Lecce, the closest station to the city. For your trip from Frosinone to Lecce by train you can choose to leave from one of Frosinone main stations: Frosinone If travelling with Trenitalia, you need to know the Frosinone to Lecce train schedule: the first train leaves at 06:43, while the last ride is at 16:07. A Frosinone to Lecce train cost about 57.1 €. But how long is the train ride from Frosinone to Lecce? Your journey takes about 7 hours on average.