Genoa to Caltagirone trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 1 daily rides to get from Genoa to Caltagirone. Trains leave from Genova Piazza Principe and arrive at Caltagirone every about 12 hours on average. If travelling with Trenitalia, you need to know the Genoa to Caltagirone train schedule: the first train leaves at 17:04, while the last ride is at 17:04. A Genoa to Caltagirone train cost about 296.9 €. But how long is the train ride from Genoa to Caltagirone? Your journey takes about 22 hours on average.