Genoa to Enna trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Genova Piazza Principe and arrive at Enna every about 4 hours on average. If travelling with Trenitalia, you need to know the Genoa to Enna train schedule: the first train leaves at 17:04, while the last ride is at 23:53. A Genoa to Enna train cost about 75.35 €. But how long is the train ride from Genoa to Enna? Your journey takes about 19 hours on average.