Genoa to Syracuse trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 6 daily rides to get from Genoa to Syracuse. Trains leave from Genova Piazza Principe and arrive at Siracusa every about 2 hours on average. If travelling with Trenitalia, you need to know the Genoa to Syracuse train schedule: the first train leaves at 05:51, while the last ride is at 23:53. A Genoa to Syracuse train cost about 69.0 €. But how long is the train ride from Genoa to Syracuse? Your journey takes about 18 hours on average. Trenitalia offers 1 direct trains between these two cities. Thanks to Trenitalia offers, you can save on your trip from Genoa to Syracuse and find prices starting from 59 €!