Genzano di Roma to Messina trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Lanuvio and arrive at Messina Centrale every about 6 hours on average. If travelling with Trenitalia, you need to know the Genzano di Roma to Messina train schedule: the first train leaves at 09:42, while the last ride is at 19:15. A Genzano di Roma to Messina train cost about 63.6 €. But how long is the train ride from Genzano di Roma to Messina? Your journey takes about 10 hours on average.