Giussano to Palermo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Mariano Comense and arrive at Palermo Notarbartolo every about 4 hours on average. If travelling with Trenitalia, you need to know the Giussano to Palermo train schedule: the first train leaves at 16:15, while the last ride is at 18:15. A Giussano to Palermo train cost about 110.5 €. But how long is the train ride from Giussano to Palermo? Your journey takes about 20 hours on average.