Giussano to Syracuse trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Mariano Comense and arrive at Siracusa every about 3 hours on average. If travelling with Trenitalia, you need to know the Giussano to Syracuse train schedule: the first train leaves at 07:15, while the last ride is at 18:15. A Giussano to Syracuse train cost about 108.6 €. But how long is the train ride from Giussano to Syracuse? Your journey takes about 18 hours on average.