Grosseto to Messina trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Grosseto and arrive at Messina Centrale every about 2 hours on average. If travelling with Trenitalia, you need to know the Grosseto to Messina train schedule: the first train leaves at 07:28, while the last ride is at 20:29. A Grosseto to Messina train cost about 74.05 €. But how long is the train ride from Grosseto to Messina? Your journey takes about 12 hours on average.