Grosseto to Niscemi trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Grosseto and arrive at Niscemi every about 6 hours on average. If travelling with Trenitalia, you need to know the Grosseto to Niscemi train schedule: the first train leaves at 04:19, while the last ride is at 04:19. A Grosseto to Niscemi train cost about 100.75 €. But how long is the train ride from Grosseto to Niscemi? Your journey takes about 17 hours on average.