Iesi to Niscemi trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Jesi and arrive at Niscemi every about 12 hours on average. If travelling with Trenitalia, you need to know the Iesi to Niscemi train schedule: the first train leaves at 15:52, while the last ride is at 15:52. A Iesi to Niscemi train cost about 170.65 €. But how long is the train ride from Iesi to Niscemi? Your journey takes about 1 hour on average.