Isernia to Caltagirone trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 1 daily rides to get from Isernia to Caltagirone. Trains leave from Isernia and arrive at Caltagirone every about 12 hours on average. If travelling with Trenitalia, you need to know the Isernia to Caltagirone train schedule: the first train leaves at 18:58, while the last ride is at 18:58. A Isernia to Caltagirone train cost about 103.25 €. But how long is the train ride from Isernia to Caltagirone? Your journey takes about 20 hours on average.