Isernia to Cosenza trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Isernia and arrive at Cosenza every about 6 hours on average. If travelling with Trenitalia, you need to know the Isernia to Cosenza train schedule: the first train leaves at 08:25, while the last ride is at 14:11. A Isernia to Cosenza train cost about 23.3 €. But how long is the train ride from Isernia to Cosenza? Your journey takes about 7 hours on average.