Isernia to Siderno trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Isernia and arrive at Siderno every about 4 hours on average. If travelling with Trenitalia, you need to know the Isernia to Siderno train schedule: the first train leaves at 07:27, while the last ride is at 18:58. A Isernia to Siderno train cost about 61.3 €. But how long is the train ride from Isernia to Siderno? Your journey takes about 11 hours on average.