Isernia to Treviglio trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Isernia and arrive at Treviglio every about 1 hour on average. If travelling with Trenitalia, you need to know the Isernia to Treviglio train schedule: the first train leaves at 06:45, while the last ride is at 15:10. A Isernia to Treviglio train cost about 105.2 €. But how long is the train ride from Isernia to Treviglio? Your journey takes about 7 hours on average.