La Spezia to Agrigento trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from La Spezia Centrale and arrive at Agrigento Centrale every about 4 hours on average. If travelling with Trenitalia, you need to know the La Spezia to Agrigento train schedule: the first train leaves at 18:18, while the last ride is at 23:47. A La Spezia to Agrigento train cost about 97.0 €. But how long is the train ride from La Spezia to Agrigento? Your journey takes about 21 hours on average. Thanks to Trenitalia, offers, you can save on your trip from La Spezia to Agrigento and find low cost tickets starting from 87 €!