Ladispoli to Manfredonia trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Ladispoli-Cerveteri and arrive at Manfredonia every about 6 hours on average. If travelling with Trenitalia, you need to know the Ladispoli to Manfredonia train schedule: the first train leaves at 09:25, while the last ride is at 13:24. A Ladispoli to Manfredonia train cost about 50.9 €. But how long is the train ride from Ladispoli to Manfredonia? Your journey takes about 7 hours on average.