Lissone to Castelvetrano trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Lissone-Muggio' and arrive at Castelvetrano every about 2 hours on average. If travelling with Trenitalia, you need to know the Lissone to Castelvetrano train schedule: the first train leaves at 07:27, while the last ride is at 22:18. A Lissone to Castelvetrano train cost about 115.85 €. But how long is the train ride from Lissone to Castelvetrano? Your journey takes about 12 hours on average.