Lissone to Enna trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Lissone-Muggio' and arrive at Enna every about 4 hours on average. If travelling with Trenitalia, you need to know the Lissone to Enna train schedule: the first train leaves at 16:27, while the last ride is at 19:27. A Lissone to Enna train cost about 70.35 €. But how long is the train ride from Lissone to Enna? Your journey takes about 19 hours on average.