Mazara del Vallo to Alessandria trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Mazara del Vallo and arrive at Alessandria every about 4 hours on average. If travelling with Trenitalia, you need to know the Mazara del Vallo to Alessandria train schedule: the first train leaves at 06:36, while the last ride is at 09:29. A Mazara del Vallo to Alessandria train cost about 131.85 €. But how long is the train ride from Mazara del Vallo to Alessandria? Your journey takes about 8 hours on average.