Mazara del Vallo to Messina trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Mazara del Vallo and arrive at Messina Centrale every about 4 hours on average. If travelling with Trenitalia, you need to know the Mazara del Vallo to Messina train schedule: the first train leaves at 06:36, while the last ride is at 16:46. A Mazara del Vallo to Messina train cost about 16.8 €. But how long is the train ride from Mazara del Vallo to Messina? Your journey takes about 6 hours on average.