Melegnano to Caltanissetta trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Melegnano and arrive at Caltanissetta Centrale every about 4 hours on average. If travelling with Trenitalia, you need to know the Melegnano to Caltanissetta train schedule: the first train leaves at 16:38, while the last ride is at 19:08. A Melegnano to Caltanissetta train cost about 124.6 €. But how long is the train ride from Melegnano to Caltanissetta? Your journey takes about 19 hours on average.