Melegnano to Enna trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Melegnano and arrive at Enna every about 6 hours on average. If travelling with Trenitalia, you need to know the Melegnano to Enna train schedule: the first train leaves at 16:38, while the last ride is at 18:07. A Melegnano to Enna train cost about 192.05 €. But how long is the train ride from Melegnano to Enna? Your journey takes about 18 hours on average.