Melito di Napoli to Marsala trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Frattamaggiore-Grumo and arrive at Mozia-Birgi every about 6 hours on average. If travelling with Trenitalia, you need to know the Melito di Napoli to Marsala train schedule: the first train leaves at 21:43, while the last ride is at 22:04. A Melito di Napoli to Marsala train cost about 99.65 €. But how long is the train ride from Melito di Napoli to Marsala? Your journey takes about 16 hours on average.