Mesagne to Altamura trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Mesagne and arrive at Altamura every about 2 hours on average. If travelling with Trenitalia, you need to know the Mesagne to Altamura train schedule: the first train leaves at 07:04, while the last ride is at 15:44. A Mesagne to Altamura train cost about 11.2 €. But how long is the train ride from Mesagne to Altamura? Your journey takes about 4 hours on average.