Mesagne to Marsala trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Mesagne and arrive at Mozia-Birgi every about 12 hours on average. If travelling with Trenitalia, you need to know the Mesagne to Marsala train schedule: the first train leaves at 11:01, while the last ride is at 11:01. A Mesagne to Marsala train cost about 113.8 €. But how long is the train ride from Mesagne to Marsala? Your journey takes about 3 hours on average.