Mesagne to Trieste trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Mesagne and arrive at Trieste Centrale every about 2 hours on average. If travelling with Trenitalia, you need to know the Mesagne to Trieste train schedule: the first train leaves at 07:05, while the last ride is at 15:44. A Mesagne to Trieste train cost about 97.05 €. But how long is the train ride from Mesagne to Trieste? Your journey takes about 13 hours on average.