Mesagne to Vasto trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Mesagne and arrive at Porto di Vasto every about 6 hours on average. If travelling with Trenitalia, you need to know the Mesagne to Vasto train schedule: the first train leaves at 07:05, while the last ride is at 13:35. A Mesagne to Vasto train cost about 34.3 €. But how long is the train ride from Mesagne to Vasto? Your journey takes about 6 hours on average.