Messina to Agrigento trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 8 daily rides to get from Messina to Agrigento. The first train to Agrigento leaves from Messina at 07:08 and the last train departs at 17:25. If you choose a local train the trip lasts on average 04:57 hours. For your trip from Messina to Agrigento by train you can choose to leave from one of Messina main stations: Messina Centrale On Wanderio you can compare all schedules, fares and railway companies to Agrigento and book the best itinerary starting from Messina.