Mestre to Alpignano trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 22 daily rides to get from Mestre to Alpignano. Trains leave from Milano Porta Garibaldi and arrive at Alpignano every 60 minutes on average. The trip by train from Mestre to Alpignano last on average 01:53 travelling with high-speed trains (Frecciarossa or Italotreno) If travelling with Trenitalia, you need to know the Mestre to Alpignano train schedule: the first train leaves at 06:40, while the last ride is at 19:48. A Mestre to Alpignano train cost about 12.2 €. But how long is the train ride from Mestre to Alpignano? Your journey takes about 2 hours on average. Thanks to Trenitalia offers, you can save on your trip from Mestre to Alpignano and find prices starting from 12 €!