Mestre to Reggio Calabria trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Venezia S. Lucia and arrive at Reggio di Calabria Centrale every 60 minutes on average. If travelling with Trenitalia, you need to know the Mestre to Reggio Calabria train schedule: the first train leaves at 00:08, while the last ride is at 19:42. A Mestre to Reggio Calabria train cost about 80.30 €. But how long is the train ride from Mestre to Reggio Calabria? Your journey takes about 14 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Mestre to Reggio Calabria and find low cost tickets starting from 62 €! If you need to travel this week, prices start from 80.30€.